The Archives: FEST 2012

Dr. Ian Pavord

Lecture Abstract: Phenotype Specific Management of Severe Asthma

I will propose that the optimum management of severe asthma requires an in depth analysis of the factors responsible for continued morbidity and a targeted approach to treatment. In most cases this required non-invasive assessment of airway inflammation and identification of the inflammatory phenotype. This approach is particularly important in patients with severe disease as phenotype diversity is greatest, the stakes are higher and the effect of current and new treatments is phenotype specific. I will outline new approaches to phenotyping airway disease using cluster analysis and speculate on the clinical relevance of this work. Finally, I will discuss new phenotype-specific treatment options.

About Ian Douglas Pavord

Ian D Pavord, DM FRCP, has been a Consultant Physician since 1995 and Honorary Professor of Medicine since 2005 at the Institute for Lung Health, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.

He trained at University College London and Westminster Hospital, graduating in 1984. As a postgraduate he has worked in Respiratory Medicine at all grades and was a Lecturer in Respiratory Medicine at Nottingham University and a Visiting Fellow at the Firestone Regional Chest and Allergy Unit, McMaster University, Canada. His research interests include the non-invasive assessment of airway inflammation in asthma, cough, and chronic obstructive pulmonary disease. He has identified a number of clinically important phenotypes of inflammatory airway disease and has played a key role in the development of new phenotype specific treatments.

Professor Pavord is the current joint Editor of Thorax, a former Associate Editor of the American Journal of Respiratory and Critical Care Medicine and Chief Medical Officer for Asthma UK. He is the author of 210 publications including 4 in the New England Journal of Medicine and 8 in the Lancet. He is the senior author of 3 of the 20 most cited papers in asthma over the last 10 years. He gave the  Cournand Lecture at the 2004 European Respiratory Society meeting, the second UK based researcher to have been given this honour. He is married to a Consultant Haematologist and has three children. He is a keen golfer with a handicap of 4.